Synthesis, identification and Study of the Biological Activity for Some New Azomethine Complexes Based on 1,8-Diaminonaphthalene
Two bidentate azomethine (Schiff bases) ligands (L1 and L2) have been formed by reacting of 6-methoxy-2-naphthaldehyde or 4-Hydroxybenzaldeyde with 1,8-diaminonaphthalene. The formula, LMCd(SCN)4 was used to make thiocyanate complexes with two metals, M can be Co or Ni. Several techniques were used to identify the compounds such as elemental analysis, FT-IR, 1HNMR, 13CNMR, mass spectra, molar conductivity and magnetic moment. It was found that the complexes don't work as electrolytes, as shown by the molar conductance tests. Nickel complexes were found to possess diamagnetic properties and to make on a proposed square planer shape, while cobalt complexes were suggested to possess paramagnetic properties and to have a tetrahedral shape. The study included an examination of biological activity, which indicated that the ligands and their complexes have good efficacy against bacteria of Staphylococcus aureus and Bacillus subtilis, as well as against fungus of Candida albicans, compared to ceftazidime, ampicillin and ketoconazole which were used as controls.