The ecological state of the water and soil in the coastal settlements of the Araz River, in the villages Bajiravan, Javadkhanly, Shakhverdili, Shammadli and Gebektala of the Imishli region of the Republic of Azerbaijan, was studied. The compositions of the water and soil samples were investigated via mass spectrometric and radio spectrometric methods. Applying the ICP-MS method to analyze water, soil and other environmental objects provides a unique opportunity to use stable isotopic tracers to control the dissolution stage of each analyzed sample. The amounts of heavy metals and radionuclides in well water in the courtyards of the local population were determined. The degree of contamination of soil and plants in cultivated areas has been studied. The content of molybdenum, copper and manganese in some water and soil samples exceeded standard values. Concentrations of molybdenum that were many times higher than the permissible limit were recorded in the waters of the Araz River and wells with drinking water. According to the research, further pollution of the Araz River in the studied areas can cause irreparable harm not only to the population's health but also to livestock.